http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100890471-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D245-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-94 |
| filingDate | 2002-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100890471-B1 |
| titleOfInvention | Multidentate aza ligands capable of coordinating metal ions and their use in diagnosis and therapy |
| abstract | The present invention relates to compounds of formula (I) and metal elements having 20 to 31, 39, 42, 43, 44, 49, and 57 to 83 atoms and 203 Pb, 67 Ga, 68 Ga, 72 As, 111 In, 113 In , 90 Y, 97 Ru, 62 Cu, 64 Cu, 52 Fe, 52m Mn, 140 La, 175 Yb, 153 Sm, 166 Ho, 149 Pm, 177 Lu, 142 Pr, 159 Gd, 212 Bi, 47 Sc, 149 A chelate with 2-3 valent ions of a radioisotope selected from Pm, 67 Cu, 111 Ag, 199 Au, 161 Tb and 51 Cr, and salts with physiologically suitable bases or acids thereof.n n n <Formula I>n n n n n n n n Wheren n n R 1 is hydrogen, C 1 -C 20 alkyl optionally substituted with one or more carboxyl groups, C 3 -C 10 cycloalkyl, C 4 -C 20 cycloalkylalkyl, aryl, arylalkyl, or two R 1 groups are taken together To form a straight or cyclic C 2 -C 10 alkylene group or ortho-disubstituted arylene;n n n R 2 is hydrogen, C 1 -C 20 alkyl, C 3 -C 10 cycloalkyl, C 4 -C 20 cycloalkylalkyl, aryl optionally substituted with a functional group to conjugate with a suitable molecule capable of interacting with the physiological system Or arylalkyl;n n n R 3 , R 4 and R 5 may be the same or different and are hydrogen, C 1 -C 20 alkyl, C 3 -C 10 cycloalkyl, C 4 -C 20 cycloalkylalkyl, aryl, arylalkyl;n n n FG may be the same or different and may be a carboxy, -PO 3 H 2 or -RP (O) OH group, where R is hydrogen, C 1 -C 20 alkyl, C 3 -C 10 cycloalkyl, C 4 -C 20 cycloalkylalkyl, aryl, arylalkyl).n n n Multidentate Aza Ligand, Paramagnetic Ion, NMR, Contrast Agent, Chelate, Radiotherapy, Radiodiagnostic Agent |
| priorityDate | 2001-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.