http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100887785-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2004-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100887785-B1 |
| titleOfInvention | Nonpolar Photoresist Formulation for Photodynamic Therapy |
| abstract | The present invention relates to pharmaceutical liposome formulations for photodynamic therapy that are stable even when stored without the need for lyophilization and comprising a nonpolar porphyrin sensitizer and one or more phospholipids. Liposomal formulations provide a therapeutically effective amount of a photosensitizer for intravenous administration. Phospholipids can be modified by PEGylation, ie including polyethylene glycol as an integral part of the phospholipid. The liposomes formed include intracellular nonpolar photosensitizers and are useful for targeting where the nonpolar photosensitizer and the second polar material are used together. When the formulation includes the presence of monosaccharides or polyalcohols, it can be efficiently lyophilized to maintain the size of the liposome vehicle and the therapeutically effective amount of the photosensitizer content. The invention also relates to liposome compositions formed by reconstitution with an aqueous vehicle. The lyophilized formulation, reconstituted with a suitable aqueous vehicle, may also form liposomes useful for intravenous administration.n n n n Liposomes, photodynamic therapy, photosensitizers, photosensitizer formulations, liposome formulations |
| priorityDate | 2003-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.