http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100885692-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2007-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100885692-B1 |
| titleOfInvention | 2- (3-chloro-4-methoxy) anilino-4-arylthiazole derivative or pharmaceutically acceptable salt thereof, preparation method thereof and pharmaceutical composition for preventing and treating cancer containing the same as an active ingredient |
| abstract | The present invention provides a 2- (3-chloro-4-methoxy) anilino-4-arylthiazole derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical for preventing and treating cancer containing the same as an active ingredient. In particular, the 2- (3-chloro-4-methoxy) anilino-4-arylthiazole derivative represented by the following general formula (1) of the present invention is a vascular endothelial growth factor (VEGF) or epidermal growth factor By exhibiting the inhibitory effect of (EGF) receptor on tyrosine kinase, and the cytotoxic effect on cell growth factor overexpressing cancer cell lines, the pharmaceutical composition of the present invention inhibits neovascularization and cancer cell growth signaling, resulting in tumor cells It can be usefully used as an anticancer agent that inhibits the growth and metastasis of.n n n [Formula 1]n n n n n n n n (Wherein R 1 and R 2 are as defined in the specification).n n n 2- (3-chloro-4-methoxy) anilino-4-arylthiazole derivative, anticancer agent |
| priorityDate | 2007-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.