http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100884564-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0306 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-18 |
filingDate | 2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100884564-B1 |
titleOfInvention | Iduronate-2-sulfatase knockout mice and methods of use thereof |
abstract | The present invention relates to a dururonate-2-sulfatase knockout mouse and a method of manufacturing the same, and to using the durron-2-sulfatase knockout mouse as an animal model for developing a Hunter syndrome therapeutic agent. The invention also provides genetically engineered mice useful as models for common lysosomal accumulators, particularly Iduronate-2-sulfatase (IDS) defects, and tissue-specific delivery systems for the treatment and treatment of such disorders. The use of such genetically designed mice in the evaluation of therapeutics for the evaluation of the n n Eduronate-2-sulfatase, knockout, mouse, Hunter syndrome, animal model |
priorityDate | 2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.