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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
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filingDate 2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2009-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2009-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100884564-B1
titleOfInvention Iduronate-2-sulfatase knockout mice and methods of use thereof
abstract The present invention relates to a dururonate-2-sulfatase knockout mouse and a method of manufacturing the same, and to using the durron-2-sulfatase knockout mouse as an animal model for developing a Hunter syndrome therapeutic agent. The invention also provides genetically engineered mice useful as models for common lysosomal accumulators, particularly Iduronate-2-sulfatase (IDS) defects, and tissue-specific delivery systems for the treatment and treatment of such disorders. The use of such genetically designed mice in the evaluation of therapeutics for the evaluation of the n n Eduronate-2-sulfatase, knockout, mouse, Hunter syndrome, animal model
priorityDate 2006-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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