abstract |
The present invention relates to pharmaceutical compositions formulated for injection administration comprising testosterone esters, in particular testosterone undecanoate, in a vehicle comprising castor oil and a cosolvent. Upon injection of the compositions of the present invention according to a particular dosing regimen, reliable levels of testosterone in serum are achieved for a long period of time in the physiologically normal range. Thus, in hormone replacement therapy and male contraception, the physician can use the composition of the present invention without incidentally monitoring the level of testosterone in the serum.n n n n Testosterone esters, castor oils, cosolvents, intramuscular injections. |