abstract |
The present invention relates to a combination of a peroxysome proliferative activating receptor (PPAR) activator and benzoquinone and to pharmaceutical compositions for the treatment and / or prevention of diseases characterized by endothelial dysfunction such as cardiovascular diseases, stroke and myocardial infarction; It relates to a process for preparing the composition and to the use of these pharmaceutical compositions.n n n According to a preferred embodiment of the invention, the benzoquinones or their precursors are ubiquinones or their precursors, of which coenzyme Q 10 or their precursors are very preferred, and the PPAR activator is fibrate or thiazolidinedione More preferably, it is fenofibrate. |