http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100861771-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-46 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
| filingDate | 2005-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100861771-B1 |
| titleOfInvention | Balineon synthase for biosynthesis of validamycin and preparation method thereof |
| abstract | The present invention relates to a violinone synthase for biosynthesis of validamycin, dehydrogenase ValA, amine transfer enzyme derived from Streptomyces hygroscopicus var. Limoneus KCTC1717 (Aminotransferase) ValB, Trehalose-phosphate synthase ValC, dTDP-4-keto-6-deoxyhexose reductase ValD, ballyon synthase (2-epi- 5-epi-valiolone synthase) ValE, glucose phosphate adenylyl transferase (Glucose-1-phosphate adenylyltransferase) ValF has the effect of determining the gene sequence and amino acid sequence provided. In addition, physiologically active substances, including the valienamine structure, which is an intermediate of the biosynthesis of validamycin, have mainly alpha-glucosidase inhibition effect, which is why it is developed as an obesity treatment and pesticide in agriculture. As an important compound being developed, the enzymes for biosynthesizing the valenamine structure, that is, the dehydrogenase ValA, the amine transferase ValB, the ditipi keto deoxyhexose reductase (dTDP-4) The gene sequence and amino acid sequence of the -keto-6-deoxyhexose reductase) ValD, the 2-epi-5-epi-valiolone synthase ValE, are then screened for the bioactive-producing strains having a baliamine structure. In addition to the production of primers and DNA chips, it can be usefully applied for more effective production of validamycin or valenamine. Many effects can be expected.n n n n Streptomyces hygroscopius limoneus, validamycin, baliamine |
| priorityDate | 2005-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 352.