abstract |
The present invention provides the preparation of novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I), wherein R 1 , R 2 , R 3 and X are as defined in the claims, and pharmaceutical compositions To their use as active ingredients. The present invention also relates to related aspects including methods of preparing the compounds, pharmaceutical compositions containing one or more such compounds, and methods of treatment comprising administration of said composition to an animal. |