http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100847415-B1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0090c8fb4a27c0e79f945da40ea60843
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435
filingDate 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bee67233f94b82014daeb87fb509f93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c9539a1b68e007f42a4d83f126cad5
publicationDate 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100847415-B1
titleOfInvention Anticonvulsants
abstract The present invention relates to the synthesis of better anticonvulsant compounds through structural changes of existing anticonvulsants, comprising 2-substituted 8-azabicyclo [3.2.1] octan-3-one represented by the following structural formula: Provide anticonvulsants.n n n n n n n n In addition, the present invention comprises the steps of stirring a mixture of tropinone, ethanol, and water-soluble NaOH for 20 minutes at 0 ℃; Adding 2-Furaldehyde using a dropping funnel at 0 ° C .; Stirring the reaction mixture for 3 h at 0 ° C. under nitrogen (N 2 ) to precipitate the crude light brown solid; Diluting the reaction mixture with water and neutralizing with aqueous HCl; Extracting the neutralized solution with dicholoromethane; Drying, filtering and concentrating the organic layer; Providing a synthesis method comprising chromatographing the residue on silica gel to produce 2-furan-2-ylmethylene-8-methyl-8-azabicyclo [3.2.1] octan-3-one as a dark brown sticky oil. do.
priorityDate 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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