http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100847415-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0090c8fb4a27c0e79f945da40ea60843 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 |
filingDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bee67233f94b82014daeb87fb509f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c9539a1b68e007f42a4d83f126cad5 |
publicationDate | 2008-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100847415-B1 |
titleOfInvention | Anticonvulsants |
abstract | The present invention relates to the synthesis of better anticonvulsant compounds through structural changes of existing anticonvulsants, comprising 2-substituted 8-azabicyclo [3.2.1] octan-3-one represented by the following structural formula: Provide anticonvulsants.n n n n n n n n In addition, the present invention comprises the steps of stirring a mixture of tropinone, ethanol, and water-soluble NaOH for 20 minutes at 0 ℃; Adding 2-Furaldehyde using a dropping funnel at 0 ° C .; Stirring the reaction mixture for 3 h at 0 ° C. under nitrogen (N 2 ) to precipitate the crude light brown solid; Diluting the reaction mixture with water and neutralizing with aqueous HCl; Extracting the neutralized solution with dicholoromethane; Drying, filtering and concentrating the organic layer; Providing a synthesis method comprising chromatographing the residue on silica gel to produce 2-furan-2-ylmethylene-8-methyl-8-azabicyclo [3.2.1] octan-3-one as a dark brown sticky oil. do. |
priorityDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.