| abstract |
The present invention relates to novel chalcone derivatives which are low molecular weight and non-peptide-based substances as IL-5 inhibitors having a chronic allergic inflammatory effect, a method for preparing the same, and use as an interleukin-5 (IL-5) inhibitor.n n n Since the novel chalcone derivatives according to the present invention are low-molecular non-peptide-based substances, unlike the conventionally known allergic inflammation therapeutics, there is no non-specific reaction to the protein, and thus may be useful as an allergic inhibitor.n n n Allergy, Inflammation, IL-5, Inhibitor |