http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100818541-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 |
filingDate | 1999-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2008-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2008-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100818541-B1 |
titleOfInvention | 1,2-annealed quinoline derivatives |
abstract | The present invention provides a compound of formula (I) or a pharmaceutically acceptable acid addition salt or stereochemically isomeric form thereof; To a process for the preparation thereof, a composition comprising the same and a use as a medicament:n n n n n n n n Wheren n n = X 1 -X 2 -X 3 is a trivalent radical of the formula:n n n Is a trivalent radical of the formula:n n n r and s are each independently 0,1,2,3,4 or 5;n n n t is 0,1,2 or 3;n n n Each R 1 and R 2 are independently hydroxy, halo, cyano, C 1 - 6 alkyl, trihalomethyl, trihalomethyl Romero ethoxy, C 2 - 6 alkenyl, C 1 - 6 alkyloxy, hydroxy-C 1 - 6 alkyloxy, C 1 - 6 alkylthio, C 1 - 6 alkyloxy C 1 - 6 alkyloxy, C 1 - 6 alkyloxy carbonyl, amino-C 1 - 6 alkyloxy, mono- or di (C 1 -6 alkyl) amino, mono- or di (C 1-6 alkyl) amino C 1 - 6 alkyloxy, aryl, aryl C 1 - 6 alkyl, aryloxy or aryl-C 1 - 6 alkyloxy, hydroxycarbonyl, C 1 - 6 alkyloxy-carbonyl, aminocarbonyl, amino-C 1 - 6 alkyl, mono- or di (C 1-6 alkyl) aminocarbonyl, mono- or di (C 1 - 6 alkyl) amino C 1 - 6 alkyl;n n n Two R 1 or R 2 adjacent to each other on a phenyl ring may together independently form a divalent radical of the formula:n n n R 3 is hydrogen, halo, C 1 - 6 alkyl, cyano, halo C 1 - 6 alkyl, hydroxy C 1 - 6 alkyl, cyano, C 1- 6 alkyl, amino C 1 - 6 alkyl, C 1 - 6 alkyloxy C 1 - 6 alkyl, C 1 - 6 alkylthio C 1 - 6 alkyl, aminocarbonyl C 1-6 alkyl, hydroxycarbonyl, hydroxycarbonyl C 1 - 6 alkyl, C 1 - 6 alkyloxy carbonyl C 1 - 6 alkyl, C 1-6 alkylcarbonyl C 1 - 6 alkyl, C 1 - 6 alkoxycarbonyl C 1 - 6 alkyl, aryl, aryl C 1 - 6 alkyloxy C 1 - 6 alkyl, mono- or di (C 1-6 alkyl) amino C 1 - 6 alkyl or the formula -OR 10, -SR 11 or -NR 11 R 12 and;n n n R 4 is optionally substituted imidazolyl;n n n Aryl is optionally substituted phenyl or naphthalenyl.n n n 1,2-annealed, quinoline, derivative |
priorityDate | 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 266.