abstract |
Compounds of formula (I), or pharmaceutically acceptable salts or prodrugs thereof, are immunomodulators and are useful for the treatment of restenosis and immune and autoimmune diseases. In addition, cancer-, fungal proliferation-, restenosis-, post-transplant tissue rejection- and immune- and autoimmune disease-suppressive compositions, with minimal side effects due to shortened half-life, and cancer, fungal proliferation in mammals, Described are methods for inhibiting restenosis, post-transplant tissue rejection, and immune and autoimmune diseases.n n n n n n n n n n n Tetrazole-containing rapamycin analogs, immunosuppressants, immunomodulators, shortened half-lives, immune and autoimmune diseases, cancer, fungal growth, restenosis, tissue rejection after transplantation |