http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100794449-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b04b7dd8f03481c3952e9e7c54387817 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2007-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fce2598a17f88fa3e9a22b697c3a5b0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbefbc7f403b3d0363847101334632a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_274b682a66d4f9725beabb1e34b728eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d8278bcd323ac28f5b1b3728dc1eb87 |
| publicationDate | 2008-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100794449-B1 |
| titleOfInvention | Cationic Phospholipid Nanoparticle Compositions for Nucleic Acid Delivery |
| abstract | The present invention provides 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine (1,2-dioleoyl-sn-glycero-3-ethylphosphocholine, EDOPC), 3b- [N- (N ', N '-Dimethylaminoethane) -carbamyl] cholesterol (3b- [N- (N' (N ', N'-dimethylaminoethane) -cabamyl] cholesterol, DC-cholesterol) and 1,2-dipitanoyl-sn-glycero-3 A cationic phospholipid liposome composition comprising phosphoethanolamine (1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine, DPhPE), a liposome-nucleic acid complex forming a complex thereof, and a pharmaceutical composition comprising the same . The cationic phospholipid liposomes of the present invention have a nanoparticle diameter in the range of 30 to 450 nm, and are effective for reducing intracellular nucleic acid delivery ability and cytotoxicity as compared to conventional liposomes, and thus can be usefully used for gene therapy by introducing nucleic acids into cells. have. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100986604-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101085203-B1 |
| priorityDate | 2007-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 229.