http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100790514-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8518 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-27 |
| filingDate | 2005-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100790514-B1 |
| titleOfInvention | Transgenic cloned pig expressing CSF in mammary gland and method of manufacturing the same |
| abstract | The present invention relates to a transgenic cloned pig which expresses human GM-CFS in the mammary gland and a method for producing the same. More specifically, 1) separating the somatic cells from the pig embryo; 2) preparing an expression vector comprising a mammary gland specific promoter and a polynucleotide encoding a colony stimulating factor (CSF) and introducing the same into the somatic cells; 3) selecting and culturing the cloned somatic cells into which the expression vector is introduced; 4) removing the nuclei of the eggs collected from the sows and fusing them with the somatic cells; And 5) transgenic pigs expressing a CSF protein comprising the step of transplanting the fused cloned eggs into surrogate sows and giving birth to piglets and a method of manufacturing the same. Transgenic pigs prepared by the production method of the present invention can overcome problems such as post-translational modification or mass production of the existing method, and can be easily obtained by expressing hGM-CSF in the mammary gland. It is expected that it can be used as an adjuvant and leukemia treatment adjuvant and the like. |
| priorityDate | 2005-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 328.