| abstract |
The present invention relates to a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, and a medicinal use thereof:n n n n n n n n In the general formula (I), R 1 and R 2 are substituents adjacent to each other, and R 1 and R 2 together with two carbon atoms to which each of R 1 and R 2 are bonded, (1) an oxo group or (2 A 5-membered to 7-membered cyclic non-aromatic hydrocarbon ring group which may be substituted with 1 to 4 substituents selected from hydroxyl group and the like, R 3 represents a hydrogen atom and the like, and R 6 represents a hydrogen atom and the like. .n n n The compound has 5-HT1A receptor binding capacity, and the receptor antagonistic action, and is useful as a therapeutic or prophylactic agent for lower urinary tract symptoms, especially urinary tract symptoms.n n n Piperidine, indole, derivatives, lower urinary tract symptoms |