http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100783020-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate | 2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100783020-B1 |
| titleOfInvention | 2-Methylchloride Pyridine Derivative and Preparation Method of Benzimidazole Derivative Using the Same |
| abstract | The present invention relates to a 2-methylchloride pyridine derivative and a method for preparing a benzimidazole derivative using the same. Specifically, the pyridine derivative is used as a starting material for a nitration step, cyanation step, alkoxylation step, oxidation step, esterification step and halogenation. A 2-methylchloride pyridine derivative was prepared through the steps, and the 2-methylchloride pyridine derivative prepared above was condensed under a mercapto benzimidazole derivative, a borohydride exchange resin and an appropriate solvent, and oxidized with an aqueous hydrogen peroxide solution in the presence of a metal catalyst. Reaction to produce benzimidazole derivatives, the method for preparing 2-methylchloride derivatives of the present invention can be produced in high yield and the pyridine derivatives used as starting materials are safe and very inexpensive and economical, the 2-methylchloride Benzimidazole E for Gastric Ulcer Treatment The method of preparing the conductor is to suppress the formation of the side reactions in the reaction step and to obtain a high yield of the target without the general purification work, in particular the recovery and reuse of the borohydride exchange resin and metal catalyst used in the reaction It is environmentally friendly.n n n n Scheme 1n n n n n n n n (Wherein R 1 , R 2 , R 3, R ′ and X are as defined in the specification). |
| priorityDate | 2001-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.