| abstract |
In the profragment region of prorenin, a method for screening a substance capable of inhibiting the activation of prorenin using the regulation ability of prorenin activation by the interaction between proteins, and the profragment region of prorenin Prorenin activation inhibitors having a donation that inhibits the activation of prorenin based on protein-to-protein interactions, as well as suppressors, organ hypertrophy inhibitors, and arterial thickening inhibitors containing the prorenin activation inhibitors as active ingredients. to provide.n n n Prorenin, fragments, protein interactions, primary structure |