http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100774925-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df527252ebc8f8c31a1f15669f3219d1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-728 |
| filingDate | 2006-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880cf98546789977d71cb95fb000a940 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ede56da744d1f2ad3f706b2abdf300 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271d147cf2742fd4a23a8612b8582c68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b3bf36d83426cbac2aba0697688cea |
| publicationDate | 2007-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100774925-B1 |
| titleOfInvention | Nanoparticles for Target Orientation and Manufacturing Method Thereof |
| abstract | The present invention is hyaluronic acid or a salt thereof; Cu 2 +, Cu 3 +, Zn 2 +, Zn 3 +, Ni 2 +, Ni 3 +, Mg 2 +, Mg 3+, Ca 2 +, Ca 3 +, Co 2 +, Co 3 +, Ba 2 +, Ba 3 +, Fe 2 +, Fe 3 +, and the like divalent or trivalent transition metal ion or alkaline earth metal ions; And a nanoparticle having a mean particle diameter of 10 to 1,000 nm, comprising a therapeutically effective amount of an anticancer agent.n n n Nanoparticles of the present invention is a drug delivery system prepared by nanoparticles of a mixture of hyaluronic acid or a salt thereof and an anticancer agent of various structures using metal ions, the manual target orientation of the anticancer agent through the EPR effect by the nanoparticles and The affinity between hyaluronic acid and cancer cells enables active targeting of anticancer drugs simultaneously. That is, the nanoparticles according to the present invention is a nano-drug delivery system that can selectively act on cancer cells, and can selectively act on metastatic cancer as well as solid cancer. In addition, the nanoparticles of the present invention have excellent biocompatibility, high affinity for cancer cells, and physical and chemical stability. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101074026-B1 |
| priorityDate | 2006-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.