http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100774250-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
| filingDate | 2006-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100774250-B1 |
| titleOfInvention | 1,4-dihydropyridine derivative elution controlled granules, tablets thereof and preparation method thereof |
| abstract | The present invention relates to a 1,4-dihydropyridine derivative dissolution controlled granule, a tablet thereof and a method for preparing the same, (a) solubility in an effective concentration of 1,4-dihydropyridine derivative or salt thereof at a pH of 6.7 to 7.5 Granules comprising a binder liquid and a pharmaceutically acceptable carrier comprising a polymer material having a content of 0.1% (w / w) or less and a polymer material having a solubility of 2% (w / w) or more at a pH of 6.7 to 7.5; And (b) a polymer coating solution containing a polymer material having a solubility of 0.1% (w / w) or less at a pH of 1.0 to 3.5 and a polymer material having a solubility of at least 2% (w / w) at a pH of 1.0 to 3.5. Coating layer comprising; By providing a 1,4-dihydropyridine derivative elution controlled granules comprising a tablet, a tablet using the same and a method for preparing the same, the dissolution rate is precisely from the rapid fast release to the slow delayed sustained release pattern in the gastrointestinal, small intestine and large intestine environment, respectively It is possible to prepare a drug containing a 1,4-dihydropyridine derivative capable of controlling.n n n n 1,4-dihydropyridine derivative, elution controlled, solubility, high molecular weight |
| priorityDate | 2006-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.