| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf91bf3156a5354f0b54ac371da9503 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-599
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0628 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 |
| filingDate |
2006-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a816ee887ad9780c555d81cb815b282f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45e13f04f743ebad42656f4df97a356b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7109e248a1ad2e722bbc8fd273605fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_378c7858365c2b63ebd9e146d8eef7bc |
| publicationDate |
2007-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-100771171-B1 |
| titleOfInvention |
Isolation, proliferation and differentiation of hair follicle stem cells and composition for baldness |
| abstract |
The present invention relates to a method for separating and proliferating hair follicle stem cells, to differentiate them into hair follicle cells, and to a composition for treating baldness, wherein the scalp tissue including hair follicles is incised finely, and the dissected tissue is subjected to proteolysis including a DNA enzyme. Performing a first chemical decomposition in a medium containing an enzyme complex and a disparate; Performing secondary chemical degradation in a medium containing collagenase; Recovering the chemically degraded tissue and culturing the scalp cells in a medium containing 1-30% of serum, followed by culturing in serum-free medium after cell attachment; Recovering the cultured scalp cells and then separating the CD34 positive (+) cells therefrom to separate the hair follicle stem cells; And separating and proliferating the hair follicle stem cells and differentiating them into hair follicle cells, comprising administering the isolated hair follicle stem cells to the scalp tissue by subcutaneous injection and differentiating them into hair follicle cells. There is provided a composition for treating baldness.n n n The hair follicle stem cells obtained according to the present invention have the ability to differentiate into adult hair follicle cells and have the ability to grow hair, which is very useful as a novel cell therapy for hair loss. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106659741-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9820933-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101658333-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016006788-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100827252-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20140125735-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220155560-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101738536-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106659741-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011056017-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011056017-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210152094-A |
| priorityDate |
2006-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |