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publicationDate 2007-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100745990-B1
titleOfInvention Manufacturing method of micro array
abstract A method of making a microarray with improved reaction yield is provided. The method of manufacturing a microarray provides a substrate which is protected by an acid-decomposable protecting group on the surface, and which has a functional group fixed thereto capable of coupling with an oligomer probe, providing a photoacid generator on the substrate, a convex portion and A template for imprint having a plurality of recesses surrounded by the convex portions is arranged such that the convex portion is in contact with or close to the upper surface of the substrate to define a plurality of reaction spaces surrounded by the upper surface of the substrate, the convex portions and the recesses of the template for imprint, and the reaction space. Is selectively exposed to produce acid in the reaction space exposed by the photoacid generator, deprotected functional groups in the reaction space by the generated acid, and provides oligomer probes on the substrate to couple with the deprotected functional groups. It involves doing.
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