Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2000-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-100738940-B1 |
titleOfInvention |
Drugs with a protective effect against oxidative-toxic substances, especially cardiotoxic substances |
abstract |
The present invention relates to benzazine-N-acetic acid derivatives having salts of oxo groups in the α-position of the nitrogen atom and substituted at the 3-position by 1- (carboxyalkyl) -cyclopentyl-carbonyl-amino radicals, salts and biological The labile esters are directed to the use for the prevention and treatment of cardiac damage caused by cardiotoxic administration of drugs or chemicals to large mammals and in particular to humans. The present invention relates in particular to the prevention and / or treatment of heart damage, in particular myocardial damage which may occur in cell growth inhibitory chemotherapy. Furthermore, the present invention relates to the use of the benzazine-N-acetic acid derivatives for adjuvant therapeutic use in therapy in which drugs with oxidative-toxic side effects are used. The present invention also relates to the manufacture of a drug suitable for such prophylactic and / or therapeutic or adjuvant treatment. |
priorityDate |
1999-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |