| abstract |
The present invention provides genomic and nucleotide sequences encoding polypeptides of Chlamydia trachomatis , such as cellular envelope polypeptides that are secreted or specific or involved in metabolism, metabolic processes, or virulence, polypeptides encoding such sequences, And to vectors comprising said sequence and to cells and animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia trachomatis genome, such as antisense and ribozyme molecules, which can be used for example to control microbial growth. The present invention relates to a method for detecting these nucleic acids or polypeptides and to a kit for diagnosing Chlamydia trachomatis infection. The present invention relates to a method for selecting a compound capable of controlling bacterial infection and a method for biosynthesis or biodegradation of the molecule using the nucleotide sequence or polypeptide. Finally, the present invention relates to compositions for the prevention and treatment of pharmaceuticals, in particular vaccines, bacteria, in particular chlamydia trachomatis infection. |