http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100731273-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2000-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100731273-B1 |
| titleOfInvention | Respiratory synthium virus replication inhibitor |
| abstract | The present invention provides respiratory syntium virus replication inhibitors of compounds of formula (I), prodrugs, N-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; To their formulations, compositions comprising them and their use as medicaments:n n n n n n n n Wheren n n -a 1 = a 2 -a 3 = a 4 -is a divalent radical of the formula: -CH = CH-CH = CH-;-N = CH-CH = CH-;-CH = N-CH = CH-; -CH = CH-N = CH-; -CH = CH-CH = N-; Each hydrogen atom may be optionally substituted; Q represents a radical of the formula:n n n n n n n n n n n n n Wherein Alk is C 1-6 alkanediyl; Y 1 is a divalent radical of the formula -NR 2 -or -CH (NR 2 R 4 )-; X 1 is NR 4 , S, S (= O), S (= O) 2 , O, CH 2 , C (= O), C (= CH 2 ), CH (OH), CH (CH 3 ), CH (OCH 3 ), CH (SCH 3 ), CH (NR 5a R 5b ), CH 2 -NR 4 or NR 4 -CH 2 ; X 2 is a direct bond, CH 2 , C (═O), NR 4 , C 1-4 alkyl-NR 4 , NR 4 -C 1-4 alkyl; t is 2, 3, 4 or 5; u is 1, 2, 3, 4 or 5; v is 2 or 3; Here, in Alk and the radical (b-3), (b -4), (b-5), (b-6), (b-7) and (b-8) each of the hydrogen atoms in the optionally R 3 May be optionally substituted by; Provided that when R 3 is hydroxy or C 1-6 alkyloxy then R 3 is not capable of replacing a hydrogen atom at the α position relative to a nitrogen atom; G is C 1-10 alkanediyl which is directly bonded or substituted; R 1 is an optionally substituted bicyclic heterocycle; R 2 is hydrogen, formyl, C 1-6 alkylcarbonyl, Hetcarbonyl, pyrrolidinyl, piperidinyl, homopiperidinyl, N (R 6 ) 2 and optionally substituted with another substituent 3-7 cycloalkyl or C 1-10 alkyl; R 3 is hydrogen, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy, arylC 1-6 alkyl or arylC 1-6 alkyloxy; R 4 is hydrogen, C 1-6 alkyl, arylC 1-6 alkyl; R 5a , R 5b , R 5c and R 5d are each independently hydrogen or C 1-6 alkyl; R 5a and R 5b , or R 5c and R 5d together form a divalent radical of the formula — (CH 2 ) s — where s is 4 or 5; R 6 is hydrogen, C 1-4 alkyl, formyl, hydroxyC 1-6 alkyl, C 1-6 alkylcarbonyl or C 1-6 alkyloxycarbonyl; Aryl is optionally substituted phenyl; Het is pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl. |
| priorityDate | 1999-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 358.