abstract |
The anthraquinones disclosed herein are antiparasitic and are particularly useful in compositions for the prevention of Schistosoma sp. In vivo or ex vivo. Preferred anthraquinones have the structure (I) wherein R 1 , R 2 , R 3 , and R 4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted Aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combinations thereof, R is methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, 15 carbohydrate, or combinations thereof And groups containing 1 to 12 carbons such as, and halogen is I, F, Br, or Cl. |