http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100706032-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3dd361222c5a9466de839aa161b0ef6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B26B19-063 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2006-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f69c72f1368db44876e950b407c720a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c91b92a069d5a621e4a58e3bf7e8fb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dec3f0114390f3ebcc13c6efb7226441 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bf2c5813f6afb34d1a954ae8c52a057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e8a21133735ceecf16513523dc878ef |
publicationDate | 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100706032-B1 |
titleOfInvention | Genotyping Kit for the Treatment of Paclitaxel Release Stent |
abstract | The present invention relates to a genotyping kit comprising a DNA chip and an electric DNA chip capable of analyzing the genetic polymorphisms of the MDR1 gene and the MRP2 gene. The kit for genotyping of the present invention comprises (i) a gene probe capable of specifically binding to the MDR1 gene and MRP2 gene of a human having a specific genetic polymorphism, and having a nucleotide sequence of SEQ ID NOs: 43 to 48; A linker comprising oligo (dT) 15 ,-(CH 2 ) 6 -and an amine group sequentially, wherein the 5 ′ end of the electric gene probe is connected to the 3 ′ end of oligo (dT) 15 ; And a aldehyde bonded to the surface, and a solid-state DNA chip comprising a solid in which an amine group of the electric linker is linked through a aldehyde group on the surface and a Schiff's base reaction; And, (ii) fluorescently labeled deoxy nucleotides for labeling the cDNA synthesized from RNA taken from the sample. If the kit for genotyping of the present invention can predict in advance whether vascular restenosis will occur in a patient who has undergone a paclitaxel release stent, the kit may be widely used for a safer stent procedure.n n n MDR1 gene, MRP2 gene, DNA chip, genotyping kit |
priorityDate | 2006-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.