| abstract |
The present invention relates to oral preparations containing silinidipine and a method for preparing the same. More specifically, the present invention relates to α-hydro-ω-hydroxypoly (oxyethylene) in order to increase bioavailability of the antihypertensive agent silnidipine which is poorly soluble in water. Solubilized solid dispersion using a poly (oxypropylene) poly (oxyethylene) block copolymer [α-Hydro-ω-hydroxypoly (oxyethylene) poly (oxypropylene) poly (oxyethylene) block copolymer, Poloxamer] as a solubilizer and binder The present invention relates to an oral preparation and a method for preparing the same, which are powdered using a stabilizer in a sieve, and mixed with a disintegrant, which does not require the use of a solvent as compared to the prior art, and thus can be formulated with high productivity.n n n n Silnidipine, solubilizer, polymer base, stabilizer, disintegrant |