http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100694994-B1

Outgoing Links

Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535
filingDate 2005-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100694994-B1
titleOfInvention Human granulocyte colony forming factor homologue
abstract The present invention relates to a novel physiologically active protein produced for enhancing the in vivo persistence of human granulocyte colony forming factors, and to a human granulocyte colony forming factor homologue which combines a polypeptide and a polyethylene glycol (PEG) polymer which is not a polypeptide component. . In the present invention, it is possible to bind polyethylene glycol to a specific site of the polypeptide while selecting a site that does not affect the activity of the protein, perform the modification of the amino acid for this portion to cysteine, and the polyethylene bond at this modified position It is characterized by the above-mentioned. The present invention also provides a pharmaceutical composition comprising the homolog, a gene encoding them, a primer for changing an amino acid sequence, and the like.n n n n Human granulocyte colony forming factor, persistence in body, polyethylene glycol, PEG, cysteine substitution
priorityDate 2005-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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