| abstract |
The present invention relates to a composition for the prevention and treatment of osteoporosis, including narrow leaf striations and extracts and fractions representing IL-6 and COX-2 expression, which are the subjects of osteoporosis reaction. More specifically, the narrow leaf periphery of the present invention and extracts and fractions exhibit an inhibitory effect on TRAP levels, which is an indicator of IL-6 and COX-2 inhibition and osteoclast formation in IL-1β-induced osteoporosis, It has excellent inhibitory effect on INF-γ involved in osteoclast formation and can be used as a medicine and health supplement for preventing and treating osteoporosis.n n n n Narrow leaf stem, IL-1β, IL-6, COX-2, TRAP, INF-γ, pharmaceutical composition, dietary supplement |