| abstract |
Objectives of the present invention include depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorders, hypertension, gastric disease, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cerebral infarction, inflammation, immune related diseases, alopecia, irritability It is to provide an antagonist for CRF receptors that is effective as a therapeutic or prophylactic agent for a condition in which CRF is thought to be involved, such as colorectal syndrome, sleep disorders, epilepsy, dermatitis, schizophrenia and the like.n n n [solution]n n n Pyrrolopyrimidine or pyrrolopyridine derivatives substituted with cyclic amino groups, represented by the formula (I) below, have a high affinity for the CRF receptor and are effective against diseases in which CRF is believed to be involved.n n n <Formula I>n n n n n n n n Pyrrolopyrimidine, Pyrrolopyridine, Cyclic amino group, CrF receptor |