abstract |
Provided are drugs for the treatment of diseases that specifically act on target cells or tissues using protein hollow nanoparticles, and agents which can efficiently contain protein drugs in the particles and methods of treatment using the drugs. In hollow nanoparticles composed of proteins (eg, hepatitis B virus surface antigen proteins) that have the ability to recognize specific cells such as hepatocytes and have particle forming ability, cell-introducing substances for disease treatment (e.g., For example, interferon or hepatocyte growth factor). |