http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100680066-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84a505a4e457d47e713b8ec47125fec1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43504 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 |
| filingDate | 2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b4a69d0904e418b6d9a54418d09603 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73893871e319c9979aae24aa03d93134 |
| publicationDate | 2007-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100680066-B1 |
| titleOfInvention | Isolation of Mussel Antioxidant Peptides from Hydrolysates Using Gastric-Intestinal Digestion System |
| abstract | The present invention relates to a method for separating mussel antioxidant peptides from a hydrolyzate using a gastro-intestinal digestion system, and more specifically, by mixing mussel proteins and water to adjust the pH to the same digestive conditions of the stomach (胃) 1 For teasing, Pepsin is first hydrolyzed under the same conditions as the digestive conditions of the stomach; The hydrolyzate obtained through primary hydrolysis was mixed with bile salt mixture, 1M calcium chloride, 0.25M Bistris, and 0.1% porcine pancreatic lipase to adjust the pH of the secondary substrate, which was adjusted to trypsin ( trypsin) and alpha-chymotrypsin are secondary hydrolyzed to small molecule peptides in an environment similar to the digestive conditions of the small intestine; The hydrolyzate obtained through secondary hydrolysis was subjected to centrifugation and dialysis and then lyophilized to obtain a mussel hydrolyzate obtained by gastric-intestinal digestion system, followed by ion exchange liquid chromatography (Ion exchange LC: Liquid Chromatography, Gel filtration LC, and C18 Reversed Phase LC for three successive purification steps; It is characterized by the separation of a single peptide showing the strongest antioxidant power, which not only shows superior lipid peroxidation inhibitory activity than conventional natural antioxidants, but also effectively alleviates or eliminates the toxicity of reactive oxygen species, radicals and peroxides. -Isolation method of mussel antioxidant peptide from hydrolyzate using small intestine digestion system. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101147847-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20120049044-A |
| priorityDate | 2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.