| abstract |
The present invention relates to compounds comprising the formula (I) or salts, esters thereof, in the inhibition of enzymes where the preferred mode of action catalyzes the hydrolysis of ester functional groups, for example in the control and inhibition of unwanted enzymes in products and processes, It relates to the use of amides or prodrugs.n n n Formula In n n n n n n n The compounds are also useful for the treatment of medicines such as obesity and related symptoms. The present invention also relates to novel compounds included in formula (I), methods for their preparation and pharmaceutical compositions containing them. In formula (I), A is a 6-membered aromatic or heteroaromatic ring, R 1 is branched or unbranched alkyl (optionally blocked by one or more oxygen atoms), alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl , Arylalkyl, fully saturated or partially saturated arylalkyl, arylalkenyl, heteroaryl, heteroarylalkyl, heteroarylalkenyl, fully saturated or partially saturated aryl, fully saturated or partially saturated heteroaryl, fully saturated or partially Saturated heteroarylalkyl, or substituted derivatives of any of these groups. |