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filingDate 2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100676123-B1
titleOfInvention Morphine sulfate micro granules, preparation method thereof, and composition containing same
abstract The present invention relates to sustained release oral formulations of the novel morphine sulfate in micro granule form.n n n In the micro granules comprising the neutral support particles coated with the active layer and the sustained release layer, the sustained release layer is a copolymer and hydrophobic of methacrylic acid and methyl methacrylate ester having a relative ratio of free carboxyl group and ester group of about 0.5 It is characterized by containing a silica showing.n n n The present invention also relates to a process for the preparation of micro granules which is carried out only in an aqueous medium by standing on neutral support particles.
priorityDate 1999-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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