abstract |
The present invention relates to an anti-HIV agent containing a 4-oxoquinoline compound of formula [I] or a pharmaceutically acceptable salt thereof as an active ingredient:n n n n n n n n Wherein each symbol is as defined in the specification.n n n The compounds of the present invention have an HIV integrase inhibitory action and are useful as anti-HIV agents for preventing or treating AIDS. In addition, when combined with other anti-HIV agents such as protease inhibitors, reverse transcriptase inhibitors, the compounds may be more effective anti-HIV agents. Because the compounds have a high inhibitory activity specific to integrase, they can provide safe drugs with fewer side effects to humans. |