http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100651393-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-08 |
filingDate | 2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2006-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100651393-B1 |
titleOfInvention | Method for preparing (R) -1-amino-2-propanol using hydrolase |
abstract | The present invention relates to a method for preparing (R) -1-amino-2-propanol using a hydrolase, and more particularly, racemic 1-azido- by reacting propylene oxide with sodium azide and ammonium chloride. Obtaining 2-propanol; Reacting the racemic 1-azido-2-propanol with acetic anhydride in the presence of a catalyst to obtain racemic acetic acid 2-azido-1-methyl-ethyl ester; Reacting the hydrolase and the racemic acetic acid 2-azido-1-methyl-ethyl ester in a buffer to obtain (R) -1-azido-2-propanol having optical activity; And reducing the azide group of (R) -1-azido-2-propanol to an amino group through a hydrogenation reaction in the presence of a palladium / carbon catalyst. It relates to a method for preparing 2-propanol. The method of the present invention provides (R) -1-amino-2-propanol having high optical purity of up to 97.7%, which is economical compared to the conventional method using very low cost propylene oxide as starting material.n n n Hydrolysis, enzyme, ester, azido, amino, propanol, optical activity |
priorityDate | 2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.