http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100638709-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5375 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 |
| filingDate | 2004-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100638709-B1 |
| titleOfInvention | N-substituted sulfamoylbenzoic acid derivatives, preparation method thereof and pharmaceutical composition for antiviral comprising the same |
| abstract | The present invention relates to an N -substituted-sulfamoylbenzoic acid derivative useful as an antiviral agent, and more particularly, a novel N represented by the following Chemical Formula 1 having an excellent antiproliferative effect of Hepatitis C virus (HCV). The present invention relates to a -substituted-sulfamoylbenzoic acid derivative, a pharmaceutically acceptable salt thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an active ingredient. The novel N -substituted-sulfamoylbenzoic acid derivatives represented by the general formula (1) according to the present invention are excellent in inhibiting the proliferation of hepatitis C virus (HCV) and have low toxicity, thus preventing and treating hepatitis C. It can be usefully used as.n n n [Formula 1]n n n n n n n n In Formula 1, R 1 represents a hydroxyl group or a -NR 2 R 3 group.n n n In the substituent for R 1 , R 2 represents a hydrogen atom, a C 1 -C 4 straight or crushed alkyl group, or a-(CH 2 ) m -R 4 group, and in the substituent for R 2 , R 4 represents a phenyl group or a heterocyclic ring, and m represents an integer of 0 to 4.n n n And, in the substituents representing R 1, R 3 is C 1 - C 4 straight or branched chain of the alkyl group, or - (CH 2) n -R 5 represents a group, in the substituent indicates the R 3, R 5 is a C A dialkylamino group of 2 -C 6 , a heterocyclic ring, or a heterocyclic ring in which a straight or pulverized alkyl group of C 1 -C 4 is substituted, n represents an integer of 0 to 4.n n n Antiviral agents, N-substituted-sulfamoylbenzoic acid derivatives, hepatitis C virus, HCV, pharmaceutically acceptable salts, antivirals, pharmaceutical compositions, hepatitis C, prophylaxis, treatment |
| priorityDate | 2004-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 374.