http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100632800-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-84 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-84 |
| filingDate | 2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100632800-B1 |
| titleOfInvention | Novel hydroxyamide derivatives having histone deacetylase inhibitory activity and preparation method thereof |
| abstract | The present invention relates to a novel hydroxyamide derivative compound of Formula 1 or a pharmaceutically acceptable salt thereof, a method for preparing the same, and an anticancer composition containing the same, wherein the novel compound of Formula 1 is an anticancer agent and histone diacetyl It can be usefully used as a prophylactic and therapeutic agent for various diseases caused by the enzymatic activity of histone deacetylase.n n n <Formula 1>n n n n n n n n Wheren n n A is C═O or CH 2 ,n n n R 1 is a phenyl group substituted or unsubstituted with hydroxy, C 1-5 alkyl, C 1-5 alkyloxy, aryl oxy, aryl amino, C 1-5 alkylamino, cyano, cyanophenyl; Naphthyl group; Halogen, C 1-5 alkyl, C 1-5 alkyloxy, C 1-5 alkylamino, C 1-5 alkylaminooxy, C 1-5 alkylarylamino, C 1-5 alkylaryloxyamino or arylmercapto A substituted or unsubstituted, heteroaryl group containing nitrogen, sulfur or oxygen in the ring, wherein the heteroaryl group is piperazine, triazole, thiazole, benzothiazole, dibenzofuran, pyridine, quinoline, or iso Quinoline;n n n R 2 is a hydroxyamino group. |
| priorityDate | 2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.