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filingDate 2005-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2006-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cae36ab901400e7dfc62e9a32c65ac1
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publicationDate 2006-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100612895-B1
titleOfInvention Selective removal of proteins from biological samples using chemicals
abstract The present invention provides a compound of formula I in a biological sample comprising a protein:n n n [Formula I]n n n n n n n n [Wherein, R 1 , R 2 , and R 3 are each independently a hydrogen atom or a substituted or unsubstituted alkyl group having 1 to 6 carbon atoms, and a is an integer of 1 to 6, provided that the amine is two or more alkyl groups And a protein nucleating agent; Treating the mixture with a hydrophobic surface material; And separating the sample from the hydrophobic surface material to which the protein is bound, while maintaining the nucleic acid in the biological sample. According to the present invention, the protein can be efficiently removed from the biological sample containing the protein, and the nucleic acid can be selectively removed by allowing the nucleic acid to be present in the sample.
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