| abstract |
The present invention relates to a compound of formula (I), its N-oxide form, pharmaceutically acceptable addition salts and stereochemically isomeric forms having a large therapeutic range:n n n n n n n n Wheren n n R 1 is hydrogen, optionally substituted C 1-6 alkyl, aryl;n n n Each R 2 is independently halogen, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy or nitro;n n n n is 0, 1, 2 or 3;n n n Alk is C 1-6 alkanediyl;n n n D is an optionally substituted saturated or unsaturated nitrogen containing heterocycle;n n n Aryl is optionally substituted phenyl.n n n The invention also relates to its use as a medicament, to its preparation and to a composition containing the same. |