http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100593707-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-005
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-00
filingDate 2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2007-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-100593707-B1
titleOfInvention Cosmetic composition applied to the surface of the skin to prevent acne and excess sebum secretion and improve acne skin, seborrheic skin and the like and a method of manufacturing the same
abstract The present invention relates to a cosmetic composition having a therapeutic effect on skin diseases caused by acne improvement and excess sebum secretion by inhibiting the activity of 5αReductase by being applied to the skin surface to prevent excessive sebum secretion and inhibiting and sterilizing bacterial growth. . First, the useful ingredient Sepicontrol A5 (INCI name: Capryloyl Glycine and Sarcosine and Cinnamomum Zeylanicum Bark Extract) was dissolved in DI water, and then soluble in Glucose / Methyl rapeseedate metabolite of Candida bombicola strain having antibacterial activity against acne-causing strains in ethyl alcohol. After compounding the agent, it is solubilized by addition to the solution. Next, Acnet (INCI name: Water and Butylene Glycol and PEG-60 Almond Glycerides and Caprylyl Glycol and Glycerine and Carbomer and Nordihydroguaiaretic Acid and Oleanolic Acid) is added and dissolved to finally release excess sebum and skin diseases such as acne. Make a cosmetic composition having a therapeutic effect. The composition is basically composed of components having antibacterial activity. Sepicontrol A5 and Acnet show excellent antimicrobial activity against Propionibacterium acnes , which is considered as the main cause of acne, and in the present invention, the effect shows synergistic effect with other components, which is an antibiotic erythromycin. (Erythtomycin) or Clindamycin was larger than.n n n In the process of sebum oversecretion, the importance of 5α Reductase is clearly shown. Excessive production of testosterone and abnormal effects of 5α reductase leads to excessive secretion of sebum, which eventually affects not only the occurrence of acne but also the deterioration of acne and seborrheic dermatitis. Accordingly, the present invention is a cosmetic composition having the property of inhibiting 5α Reductase and consequently preventing excessive secretion of sebum to reduce the occurrence and exacerbation of acne and seborrheic dermatitis. It also minimizes skin irritation caused by natural antibacterial ingredients by prescribing Witch Hazel Extract, Iricalmin (INCI name: Water, Wheat Germ Extract, Saccharomyces Cerevisiae Extract, Sodium Hyaluronate). Through the present invention, the primary effect was shown by inhibiting the growth and growth of microorganisms involved in skin acne development and skin inflammation, and secondly by inhibiting excess sebum branch which is one of the causes of acne. It solved the problem of skin seborrhea. In addition, the conventional acne cosmetic composition also contains a high content of alcohol component has the advantage that can be used without burden compared to the severe irritation or inverse smell. In fact, in vitro tests showed excellent antimicrobial activity with the composition consisting of these prescriptions, and in the human experiments on acne patients, the majority of acne patients showed clear improvement in symptoms before and after application. In addition, it was found that there is a definite effect on sebum secretion by showing a clear difference in the amount of sebum secretion before and after application. In particular, the treatment of acne requires long-term use, so that the composition containing the antibiotics or steroids may have side effects such as resistance and skin atrophy, but the present invention can exhibit such excellent effects but can exclude these side effects. There is an advantage.n n n n Acne, sebum, excess sebum secretion, antibacterial activity, antibacterial effect, side effects, acne treatment, Propionibacterium acnes, oily skin, seborrheic skin, acne skin, seborrhea, 5α Reductase, testosterone, active male hormone (DHT), antibiotic, steroid
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102506821-B1
priorityDate 2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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