http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100593238-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
filingDate | 1998-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2006-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100593238-B1 |
titleOfInvention | Vitamin D3 derivatives and therapeutic agents for inflammatory respiratory diseases prepared therefrom |
abstract | The present invention relates to a compound of formula 1 and a method for preparing the same.n n n Formula 1n n n n n n n n In Formula 1 above,n n n R 1 and R 2 are a hydrogen atom, a trialkylsilyl group, an acetyl group, a methoxymethyl group or a tetrahydropyranyl group, n is an integer from 0 to 2, Z represents Formula 1a, 1b or 1c: Formula 1a Formula 1b Formula 1c n n n In the above formula,n n n R 3 and R 4 are a hydrogen atom, a hydroxyl group, an acyloxy group, an alkyloxy group, an alkylthio group, or an alkyl group which may be substituted,n n n R 5 , R 6 , R 7 and R 8 are hydrogen atom, hydroxyl group, alkyl group or acyloxy group,n n n R 9 is a hydrogen atom, a hydroxyl group, an alkyl group or an alkylthio group,n n n R 10 is a hydrogen atom, an alkyl group or an alkyloxy group,n n n A and B are hydrogen atoms or hydroxyl groups, or they are bonded together to represent a single bond,n n n X and Y are carbonyl oxygen, one of them is a hydrogen atom, the other is a hydroxyl group or an acyloxy group,n n n m is an integer of 0-2.n n n This compound is an active ingredient for treating inflammatory respiratory disease, malignant tumors, rheumatoid arthritis, osteoporosis, diabetes mellitus, hypertension, alopecia, acne, psoriasis, dermatitis.n n n Vitamin D3 derivative of formula 1, therapeutic agent for inflammatory respiratory disease, inhibitory effect on neutrophil infiltration, induction of cell differentiation, inhibitory effect on cell proliferation, treatment of malignant tumor |
priorityDate | 1997-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.