abstract |
The present invention relates to the following novel compounds.n n n Formula 25.0n n n n n n n n Formula 29.0n n n n n n n n Formula 38.0n n n n n n n n Chemical Formula 42.0n n n n n n n n Formula 47.0n n n n n n n n Chemical Formula 53.0n n n n n n n n The present invention also relates to methods of inhibiting abnormal growth of cells, methods of inhibiting farnesyl protein transferase, and methods of treating cancer using the novel compounds.n n n Tricyclic amide compounds, farnesyl protein transferase, abnormal growth of cells, activated Ras oncogene, FPT IC50 |