| abstract |
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable addition salt thereof, wherein the compound is a dopamine D4 (anti) antagonist and is useful for treating schizophrenia, psychotic depression and manic diseases:n n n Formula (I) n n n Wheren n n R 1 is halogen or C 1 -C 4 alkyl;n n n R 2 and R 3 are the same or different and are hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, alkylthio, hydroxy, amino, mono (C 1 -C 4 ) alkylamino, di ( C 1 -C 4 ) alkylamino, orn n n R 2 and R 3 together are an alkenylene moiety having 4 carbon atoms which together with the phenyl ring form a naphthyl moiety. |