http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100570419-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F17C2221-032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F17C2260-015 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F17C13-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/F17C13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B21D51-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
filingDate | 2004-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-100570419-B1 |
titleOfInvention | Sustained-release pellet composition for oral administration of tamsulosin hydrochloric acid and preparation method thereof |
abstract | The present invention relates to a sustained release pellet composition for oral administration of tamsulosin hydrochloride having a uniform dissolution rate, and a method for producing the same. In the present invention, (a) 300 to 1000 parts by weight of the core; (b) 1 part by weight of (iii) tamsulosin hydrochloric acid, (ii) an aqueous dispersion 1: 1 copolymer of methacrylic acid-ethyl acrylate; Water-dispersed ethyl cellulose; 200 to 600 parts by weight of the primary release controlling agent selected from water-dispersed polyvinylacetate, (iii) alginate; Microcrystalline cellulose; A primary release controlling layer comprising 0.5 to 3 parts by weight of one or more release aids selected from carboxymethylcellulose sodium; (c) a secondary release controlling layer comprising 1 to 10 parts by weight of a secondary release regulator selected from ethyl cellulose, a 1: 1 copolymer of methacrylic acid-methyl methacrylate, and a copolymer of methacrylic acid-methyl methacrylate Provided is a sustained release pellet composition for oral administration of tamsulosin hydrochloric acid consisting of; and a preparation method thereof. The hydrochloride tamsulosin sustained-release pellet of the present invention is simpler to manufacture than conventional matrix type sustained-release granules, and has a uniform particle size distribution and uniform dissolution rate, and in particular, changes the composition ratio of the primary and secondary emission control layers. The dissolution rate in the stomach and intestine can be adjusted in various ways.n n n n Pellets, Tamsulosin Hydrochloride, Tamsulosin, Sustained Release, Oral |
priorityDate | 2004-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.