http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100564000-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 2003-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-100564000-B1 |
| titleOfInvention | Gene Delivery Complexes Specific for Metastatic Cancer Cells |
| abstract | The present invention relates to a gene delivery complex having specificity for metastatic cancer cells, and more particularly, to an anionic biodegradable polymer material which can be decomposed by a cancer cell specific secretion to a conjugate of a cationic high molecular material polyethyleneimine and a nucleic acid. One new formulation of the complex relates to a metastatic cancer cell specific gene transfer complex that selectively acts on specific cancer cells secreting hydrolase. The gene delivery complex of the present invention is thought to be useful as a gene therapy model of cancer by mediating selective and effective gene transfer to metastatic cancer cells that secrete the enzymes of the anionic polymer while reducing interaction with nonspecific cells. The use thereof is not limited to metastatic cancer cells, and may be usefully used for gene therapy for cells that secrete enzymes of other anionic polymers. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101415985-B1 |
| priorityDate | 2003-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.