abstract |
The present invention solves the problems of the prior art, and provides a method for impregnating a drug capable of impregnating a drug in a short time using a carbon dioxide in a supercritical or subcritical state. It is a problem.n n n In a method of impregnating a drug into a material, a low density drug mixed phase in which a drug is mixed in carbon dioxide in a supercritical or subcritical state is formed, and then the density of the drug mixed phase is increased to high density to impregnate the drug in the material. It is characterized by.n n n n Supercritical state, subcritical state, impregnation method, carbon dioxide, diffusion coefficient, pressure fluctuation mode |