abstract |
The present invention discloses compounds of formula (1), salts and esters thereof, wherein X, X ', Z and Y are as described herein and have activity as a binding inhibitor between VCAM-1 and cell expression VLA-4. Such compounds are useful for treating diseases in which symptoms and / or damage are associated with the binding of VCAM-1 to cell expression VLA-4:n n n Formula 1 |