| abstract |
The present invention provides a novel composition for solubilizing poorly soluble drugs having mucoadhesive properties; Formulation of a poorly soluble drug comprising the solubilizing composition; And a method for preparing the composition and formulation, more specifically, the composition is composed of 4 to 90% by weight of at least one monoglyceride compound and 0.01 to 90% by weight of at least one oil. . The present invention also provides a novel composition for solubilization of poorly soluble drugs, including emulsifiers; Formulation of a drug comprising the solubilizing composition; And a method for preparing the same, wherein the composition for solubilization of a poorly soluble drug including the emulsifier is 4 to 90% by weight of at least one monoglyceride compound, and 0.01 to 90% by weight of at least one oil. And 0.01 to 90% by weight of one or more emulsifiers. The composition of the present invention is present in a liquid or semi-solid at room temperature, but is suitable as a drug delivery system because it forms a liquid having mucoadhesive properties at body temperature. |