abstract |
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ) dependent glucose dehydrogenase (s-GDH), genes encoding modified s-GDH, of s-GDH with improved substrate specificity for glucose. Mutant proteins and other applications of these s-GDH variants, in particular for determining the concentration of sugars, in particular the concentration of glucose in a sample. |